54. Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002.
Author: Werzowa J.
Journal: British Journal of Dermatology
Cell-type: Melanoma Cells
Product used: SAINT-RED

53. Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.
Author: Hui Xu
Journal:
Cell-type: HUVEC
Product used: SAINT-RED

52. Tapered microfluidic chip for the study of biochemical and mechanical response at subcellular level of endothelial cells to shear flow. [primary embryonic chicken endothelial cells]
Author: Rossi M.
Journal: Lab Chip
Cell-type: Primary embryonic chicken endothelial cells
Product used: SAINT

51. Monoclonal antibody 14C5 targets integrin vß5
Author: Burvenich I
Journal: Molecular Cancer Therapeutics
Cell-type: Colo16 cells
Product used: SAINT

50. A novel vector system for gene expression into the cornea using a particlaly dried plasmid expressing 18 basic fibroblast groth factor-syntehtic amphiphile INTERACTION -18 (SAINT-18) complex
Author: Kuo, CN
Journal: Curr Eye Res
Cell-type:
Product used: SAINT-SOLID

49. Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Author: Van Kilsdonk,
Journal: Cancer Res
Cell-type: HT1080 fibrosarcoma cells
Product used: SAINT

48. Anomalous Features of EMT during Keratinocyte Transformation.
Author: Geiger, T
Journal: Plosone
Cell-type: Primary human keratinocytes, HF1
Product used: SAINT-MIX

47. Rad54B targeting to DNA double-strand break repair sites requires complex formation with S100A11.
Author: Murzik, U
Journal: Mol Biol Cell
Cell-type: HaCaT
Product used: SAINT-RED

46. DNMT3A and DNMT3B mediate autocrine hGH repression of plakoglobin gene transcription and consequent phenotypic conversion of mammary carcinoma cells
Author: Shafiei, F
Journal: Oncogene
Cell-type: MCF-mutants
Product used: SAINT-MIX

45. Bisindolylmaleimide IX facilitates extrinsic and initiates intrinsic apoptosis in TNF-alpha-resistant human colon adenocarcinoma COLO 205 cells
Author: Pajak, B
Journal: Apoptosis
Cell-type: COLO 205
Product used: SAINT-MIX SAINT-PhD SAINT-18

44. Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.
Author: Van der Gun, BT
Journal: Int J Cancer
Cell-type: SKOV-3
Product used: SAINT-MIX

43. Protein kinase C a promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.
Author: Xu, H
Journal: Cardiovasc Res
Cell-type: HUVEC, EA.hy926
Product used: SAINT-RED

42. Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2.
Author: Van der Gun, BT
Journal: J Control Release
Cell-type: B16-F10, COS-7, HEK293A, U373MG, SKOV-3, Jurkat-T
Product used: SAINT-MIX, SAINT-PhD

41. Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: implications for intracellular bile salt transport.
Author: Pellicoro, A
Journal: Hepatology
Cell-type: Primary human fibroblasts
Product used: SAINT-MIX

40. Engineering zinc finger protein transcription factors to downregulate the epithelial glycoprotein-2 promoter as a novel anti-cancer treatment.
Author: Gommans, WM
Journal: Mol Carcinog
Cell-type: COS-7, HeLa, SKOV, SW948
Product used: SAINT-MIX

39. Transcriptional activation of p53 by Pitx1
Author: Liu, DX
Journal: Cell Death Diffe
Cell-type: MCF-7
Product used: SAINT-MIX

38. Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1
Author: Ludwiczek, S
Journal: Nat Med
Cell-type: HEK293T
Product used: SAINT

37. HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells
Author: Mohankumar, KM
Journal: Oncogene
Cell-type: MCF-7, MCF-10A, HBL100, T47D, ZR75-1, HS578T, SkBr3, 21MT, 21PT, MDA-MB-231, MDA-MB-435 andMDA-MB-468
Product used: SAINT-MIX

36. Measles virus M and F proteins associate with detergent-resistant membrane fractions and promote formation of virus-like particles.
Author: Pohl, C
Journal: J Gen Virol
Cell-type: 293 HeLa
Product used: SAINT-MIX

35. Tissue microenvironment modulates CXCR4 expression and tumor metastasis in neuroblastoma.
Author: Zhang, L
Journal: Neoplasia
Cell-type: HFK293TV
Product used: SAINT-MIX

34. Biophysical aspects of transfection, interaction with the cellular membrane and endocytosis.
Author: Zuhorn IS
Journal: Eur Biophys J
Cell-type:
Product used: SAINT-MIX, SAINT-18

33. Sugarbased geminisurfactant membrane destabilizing hexagonalphase.
Author: Wasungu, L
Journal: BiochimBiophysActa
Cell-type:
Product used: SAINT-MIX

32. TFX_sugarbased_gemini_surfactant_invivo_genetherapy.
Author: Wasungu, L
Journal: J Mol Med
Cell-type: CHO-K1
Product used: SAINT-MIX

31. Adenylyl Cyclase 6 Overexpression Decreases the Permeability of Endothelial Monolayers via Preferential Enhancement of Prostacyclin Receptor Function.
Author: Bundey, R
Journal: Mol Pharmacol
Cell-type: HUVEC
Product used: SAINT-MIX

30. Epigenetic Regulation of Human Trophoblastic Cell Migration and Invasion.
Author: Rahnama, F
Journal: Endocrinology
Cell-type: BeWo
Product used: SAINT-MIX

29. Thrombin Activates AMP-Activated Protein Kinase in Endothelial Cells via a Pathway Involving Ca2+/Calmodulin-Dependent Protein Kinase Kinase ß
Author: Stahmann, N
Journal: Mol Cell Biol
Cell-type: HUVEC
Product used: SAINT-RED

28. Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes.
Author: Derfoul, A
Journal: Stem Cells
Cell-type: Human mesenchymal stem cells
Product used: SAINT-MIX

27. The human cytomegalovirus-encoded receptor US28 increases the activity of the major immediate-early promoter/enhancer.<
Author: Boomker, J
Journal: Virus Res
Cell-type: HEK-293
Product used: SAINT-MIX

25. The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study.
Author: Kneuer, J
Journal: J of Nanoscience and Nanotechnology
Cell-type:
Product used: SAINT-18, SAINT-MIX

24. Nonbilayer Phase of Lipoplex–Membrane Mixture Determines Endosomal Escape of Genetic Cargo and Transfection Efficiency.
Author: Zuhorn IS
Journal: Molecular Therapy
Cell-type: COS-7
Product used: SAINT-MIX

23.Polymorphism of Pyridinium Amphiphiles for Gene Delivery: Influence of Ionic Strength, Helper Lipid Content, and Plasmid DNA Complexation.
Author: Scarzello, M
Journal: Biophys J
Cell-type:
Product used: SAINT-18, SAINT-MIX

22. Adiponectin inhibits endothelial synthesis of Interleukin-8.
Author: Kobashi, C
Journal: Circ Res
Cell-type: HAEC, human, primairy
Product used: SAINT-MIX

21. Targeted exon skipping in transgenic hDMD mice: a model for direct preclinical screening of human-specific antisense oligonucleotides.
Author: Bremmer-Bout, M
Journal: Mol Ther
Cell-type:
Product used: SAINT-18

20. Efficient transfer of chromosome-based DNA constructs into mammalian cells.
Author: Oberle, V
Journal: Biochim Biophys Acta
Cell-type: COS-7; A9 – murine; LMTK; B16; CHO-K1
Product used: SAINT-MIX

19. Characterization and transfection properties of lipoplexes stabilized with novel exchangeable polyethylene glycol–lipid conjugates.
Author: Rejman, J
Journal: Biochim Biophys Acta
Cell-type: B16F10
Product used: Saint-PEG conjugates and Saint-18

18. A nonviral carrier for targeted gene delivery to tumor cells.
Author: Van Zanten, J
Journal: Cancer Gene Ther
Cell-type: B16F10 – Murine Melanoma; B16C215 – Murine Melanoma; SKBR-3 – Human Breast Cancer; HT29 – Human Colon Carcinoma; H5V – Murine Endothelium
Product used: SAINT-MIX

17. Effect of plasmid copy number and sequence context upon transfection efficiency.
Author: Walker, W
Journal: J Control Release
Cell-type:
Product used: SAINT-MIX

16. In vivo characteristics of cationic liposomes as delivery vectors for gene therapy.
Author: Audouy, S
Journal: Pharm Res
Cell-type:
Product used: SAINT

15. Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions.
Author: Shi, F
Journal: Biochem J
Cell-type: CHO
Product used: Saint-PEG conjugates

14. Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.
Author: Zuhorn IS
Journal: Biophys J
Cell-type: COS-7
Product used: SAINT-MIX

13. Interference of serum with lipoplex-cell interaction: modulation of intracellular processing.
Author: Zuhorn IS
Journal: Biochim Biophys Acta
Cell-type: COS-7
Product used: SAINT-MIX

12. Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis.
Author: Zuhorn IS
Journal: J Biol Chem
Cell-type: COS-7
Product used: SAINT-MIX

11. Cationic lipid-mediated transfection in vitro and in vivo (review).
Author: Audouy S
Journal: Mol Membr Biol
Cell-type:
Product used: SAINT-MIX

10. Molecular shape of the cationic lipid controls the structure of cationic lipid/ dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery.
Author: Smisterová J
Journal: J Biol Chem
Cell-type: COS-7
Product used: SAINT-MIX

9. Efficient cationic lipid-mediated delivery of antisense oligonucleotides into eukaryotic cells: down-regulation of the corticotropin-releasing factor receptor.
Author: Shi F
Journal: Nucleic Acids Res
Cell-type: CHO
Product used: SAINT-MIX

8. An SV40 large T-antigen immortalized human umbilical vein endothelial cell line for anti-endothelial cell antibody detection.
Author: Van Leeuwen EBM
Journal: Clin Exp Rheumatol
Cell-type: HUVEC; HIVEC; HUAEC; HIAEC
Product used: SAINT-MIX

7. Serum as a modulator of lipoplex-mediated gene transfection: dependence of amphiphile, cell type and complex stability.
Author: Audouy S
Journal: J Gene Med.
Cell-type: CHO-K1 – Chinese Hamster Ovary; ECV 304 – Human Vascular Endothelium; H5V – Murine Endothelium; RCC4 – Human Renal Carcinoma; C26 – Murine Colon Carcinoma; FLF92 – Fetal Lung Fibroblast
Product used: SAINT-MIX

6. Synthesis of pyridinium amphiphiles used for transfection and some characteristics of amphiphile/DNA complex formation.
Author: Meekel AAP
Journal: Eur J Org Chem
Cell-type: COS-7
Product used: SAINT-MIX

5. Lipoplex formation under equilibrium conditions reveals a three-step mechanism.
Author: Oberle V
Journal: Biophys J
Cell-type:
Product used: Saint-2

4. In vivo evaluation of the safety and toxicity of a new cationic liposome formulation for human gene therapy applications.
Author: Audouy S
Journal: AACR meeting
Cell-type:
Product used: SAINT-MIX

3. Transfection of small numbers of human endothelial cells by electroporation and synthetic amphiphiles.
Author: Van Leeuwen EBM
Journal: Eur J Vasc Endovasc Surg
Cell-type: HUVEC
Product used: SAINT-MIX

2. Ovel pyridinium surfactants for efficient, nontoxic in vitro gene delivery.
Author: Van der Woude I
Journal: Proc Natl Acad Sci U S A
Cell-type: COS-7; CV-1; BHK - baby hamster kidney; 36C2.21 - an immortalized oligodendrocyte cell line.
Product used: Different Saint molecules, also Saint-2

1. Parameters influencing the introduction of plasmid DNA into cells by the use of synthetic amphiphiles as a carrier system.
Author: Van der Woude I
Journal: Biochim Biophys Acta
Cell-type:
Product used: Dotma DOPE