1ml SAINT-RED ( € 195,-) is sufficient to perfrom 600 tfx on a 24 well format with 4 pmol siRNA.
This comes down to a price per transfection of just € 0.35
Click below to read more about the great benefits:
- Inhibition of EpCAM expression on SKOV-3 tumour cells.
- High throughput siRNA screening. ( Max Planck Institute )
- Inhibition of enzyme activity with different amounts of siRNA.
- Long term preservation and high transfection efficacy of siRNA.
Recent SAINT-RED Articles:
Regine Heller, Qing Chang, Gunter Ehrlich.
Overlapping and distinct roles for P13Kß and Y isoforms in S1-P-induced migration
of human and mouse endothelial cells.
Murzik U, Mol Biol Cell 2008 Epub, Rad54B targeting to DNA double-strand break repair
sites requires complex formation with S100A11. (Transfection was performed using the
amphiphilic delivery system SAINT-RED(Synvolux Therapeutics B.V., Groningen, The Netherlands)
Xu H, Cardiovasc Res 2008 Vol 78:349-355. Protein kinase C a promotes angiogenic
activity of human endothelial cells via induction of vascular endothelial growth
factor. (Transfection was performed with 50nM siRNA duplexes using the amphiphilic
delivery system SAINT-RED (Synvolux Therapeutics, Groningen, The Netherlands)
according to the manufacturer’s instructions (ref Stahmann))
Bundey, Richard et al. Mol.Pharmacol. 2006 Vol 70, 1700-1707 Adenylyl Cyclase 6
Overexpression Decreases the Permeability of Endothelial Monolayers via Preferential
Enhancement of Prostacyclin Receptor Function. (Transfection of siRNA in HUVECs to
knock down gene expression using SAINT-RED)
SAINT-RED product description and protocols:
The SAINT-RED delivery system is based on a cationic pyridinium head group, showing excellent bio-compatibility.
Protocols:
SAINT-RED Protocol
SAINT-RED Sketch
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