Click below to read more about the great benefits:

  - Inhibition of EpCAM expression on SKOV-3 tumour cells.

  - High throughput siRNA screening. ( Max Planck Institute )

  - Inhibition of enzyme activity with different amounts of siRNA.

  - Long term preservation and high transfection efficacy of siRNA.

 
Recent SAINT-RED Articles:

Regine Heller, Qing Chang, Gunter Ehrlich.
Overlapping and distinct roles for P13Kß and Y isoforms in S1-P-induced migration
of human and mouse endothelial cells.

Murzik U, Mol Biol Cell 2008 Epub, Rad54B targeting to DNA double-strand break repair
sites requires complex formation with S100A11. (Transfection was performed using the
amphiphilic delivery system SAINT-RED(Synvolux Therapeutics B.V., Groningen, The Netherlands)

Xu H, Cardiovasc Res 2008 Vol 78:349-355. Protein kinase C a promotes angiogenic
activity of human endothelial cells via induction of vascular endothelial growth
factor. (Transfection was performed with 50nM siRNA duplexes using the amphiphilic
delivery system SAINT-RED (Synvolux Therapeutics, Groningen, The Netherlands)
according to the manufacturer’s instructions (ref Stahmann))

Bundey, Richard et al. Mol.Pharmacol. 2006 Vol 70, 1700-1707 Adenylyl Cyclase 6
Overexpression Decreases the Permeability of Endothelial Monolayers via Preferential
Enhancement of Prostacyclin Receptor Function. (Transfection of siRNA in HUVECs to
knock down gene expression using SAINT-RED)

 
SAINT-RED product description and protocols:

The SAINT-RED delivery system is based on a cationic pyridinium head group, showing excellent bio-compatibility.

Protocols:
SAINT-RED Protocol
SAINT-RED Sketch