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Cationic-lipid

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SAINT-Solid-1 cationic lipid SAINT-Solid-1 cationic lipid
SAINT-Solid-1 cationic lipid product description.

The SAINT-Solid-1 (1-methyl-4-(cis-9-dioleyl)methylpyridinium-chloride) cationic lipid is
now available as a solid pure compound.

Many different applications come available now for researchers to develop their own formulations. One most
intriguing possibility is the formulation of classical liposomes were one lipid is partly exchanged with saint
solid.

The example below shows the delivery of liposomal formulated calceine (classical formulation on first picture),
in comparison with the immunoliposome (second picture) and a immonutargeted SAINT-O-SOMES (third picture).

Properties and structure:

IUPAC name: 4-[(9Z,28Z)-heptatriaconta-9,28-dien-19-yl]-1-methylpyridin-1-ium chloride
- Molecular formula: C43H78ClN
- Formula weight: 644.5
- CAS registry number: 187587-97-9
- Purity (HPLC): 99%
- Appearance at 20°C and 101.3kPa: colorless sticky solid
- Calculated n-octanol/water partition co-efficient: log Pow = 11.65 at 21°C

Applications:

The cationic nature in combination with the lipid feature and the aromatic pyridine moiety
yield this molecule unique properties. These properties enable the use of this compound in many
applications, especially in the field of transfection and liposomal formulations.

Usage:

This compound may be used for research purposes only. Commercial use is prohibited.
This compound is protected by international patents EP755924, US5853694, US6726894. Licensing
information is available from Synvolux.