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Featured products at Synvolux Therapeutics:
DNA transfection reagent SAINT-MIX:
- Fully synthetic transfection reagent
- Serum transfection compatible
- Efficiencies up 96%
- Free of animal-derived components
siRNA transfection reagent SAINT-RED:
- Fully synthetic transfection reagent
- Only 4pmol siRNA needed
- Long-term siRNA storage
- Free of animal-derived components
Protein transfection reagent SAINT-PhD:
- Fully synthetic transfection reagent
- Functionality preserved
- Up to 98% efficiency
- Free of animal-derived components
Transfection is the process of introducing nucleic acids into cells by non-viral methods.
Transfection reagent allow the uptake of material. Genetic material (such as supercoiled plasmid DNA or plasmid fragments), siRNA or even proteins such as antibodies, may be transfected. In addition to transfection performed with lipoplexes, transfection can be carried out using the classical calcium phosphate transfection, electroporation devices , or by mixing a cationic lipid with the material to produce liposomes. These three classical methods induce fusion with the cell plasma membrane and endocytosis which hopefully results in the deposition of their cargo inside the cell.
Synvolux developed a new series of transfection reagents and transfection protocols which guarantee a high cell transfection efficacy combined with minimal cell death.
For plasmid DNA transfection we recommend SAINT-MIX.
Transfection of primary cells with high transfection efficacy is achieved with SAINT-18.
Normally transient transfection is achieved, however when applying a selection marker stable transfection efficacy will be high and you will easily retrieve stable cell lines expressing the protein of interest.
SiRNA transfection with minimal amounts of siRNA and maximal down-regulation of the targeted gene is achieved with SAINT-RED.
Protein transfection protcols can be found in the SAINT-PhD (Protein high Delivery) kit.
For therapeutical applications we develop the SAINT-O-SOMES methods which can be prepared by using SAINT-Solid-1.
The term transformation is preferred to describe non-viral DNA transfer in bacteria.
Our product TRAEN, TRAnsformation ENhancer, will boost your bacterial colonies retrieved after transformation by 10 times. The protocol is very friendly and extremely simple.
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